Amongst the most common congenital malformations SPINA BIFIDA or split spine is the most frequent birth defect. Looking at the total population about 4-5 children in 1,000 are affected. Therefore we recommend taking 5mg of folic acid per day starting prior to conception, and going on during the early stages of pregnancy. Please consult your doctor to discuss this matter. Thus the risk of this deformity can be reduced by 50-70%. Other malformations, such as cleft lip and palate (face), pathological alterations in the cardiovascular system in the urinary tract and the limbs can possibly be prevented by taking folic acid. Please note that this vitamin compound should be taken before conception and in the first trimester of your pregnancy.